NAD⁺ is the master cofactor at the center of cellular energy, DNA repair, and longevity science. Researchers use it when they want to understand what happens when you refill one of the most critical molecules that declines with age and metabolic stress.
How It Works
NAD⁺ cycles between NAD⁺ and NADH in glycolysis, the TCA cycle, and the electron transport chain to support ATP production. It’s also a substrate for sirtuins (regulating gene expression, mitochondrial biogenesis, and stress resistance) and PARPs (supporting DNA repair and genomic integrity). Increasing NAD⁺ availability can shift cells toward better energy production and resilience in experimental models.
Regulatory & Research Note
While NAD⁺ is naturally present in the body and oral NAD⁺ precursors are sold as supplements, injectable NAD⁺ in this context is not FDA-approved as a drug product. This material is supplied for research use only and is not for human injection or therapy.

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