AOD-9604 is the famous “fat-burning fragment” of human growth hormone, created to isolate GH’s adipose-targeting effects. It’s used in research as a tool to explore how specific segments of the GH molecule can influence fat metabolism without the full anabolic or IGF-1–dominated impact.
How It Works
AOD-9604 corresponds to amino acids 176–191 of GH. It appears to act on fat cell receptors and signaling cascades that regulate lipolysis and lipogenesis, increasing fat breakdown and inhibiting new fat storage in preclinical models. Unlike full GH, it does not significantly raise IGF-1 or trigger broad growth hormone receptor activation, making it more “fat-focused” in its mechanism.
Regulatory & Research Note
AOD-9604 is not FDA-approved for any indication as a drug. It is provided strictly as a research peptide, not for human injection, ingestion, or therapeutic use.

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